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  • Sol-Can® A Citrate

Product picture-Sol-Can® A Citrate 901
Product picture-Sol-Can® A Citrate 901
Product picture-Sol-Can® A Citrate 901

Sol-Can® A Citrate
Sol-Can® A Citrate is a citric acid hemodialysis concentrate in the mixing ratio 1+44

In general, citric acid is a natural metabolite that is processed through the citrate cycle. Citric acid is biocompatible and physiologically compatible for reliable tolerance, as citric acid is a weak organic acid that can be rapidly metabolized by the body.1 Sol-Can® A Citrate is an alternative concentrate designed to enhance comfort for patients and the entire renal care center by potentially reducing side effects and promoting patient well-being.

Read more

In general, citric acid is a natural metabolite that is processed through the citrate cycle. Citric acid is biocompatible and physiologically compatible for reliable tolerance, as citric acid is a weak organic acid that can be rapidly metabolized by the body.1 Sol-Can® A Citrate is an alternative concentrate designed to enhance comfort for patients and the entire renal care center by potentially reducing side effects and promoting patient well-being.

References

1 Safránek R, Moučka P, Vávrová J, Palička V, Pavlíková L, Sulková SD. Changes of serum calcium, magnesium and parathyroid hormone induced by hemodialysis with citrate-enriched dialysis solution. Kidney Blood Press Res. 2015;40(1):13–21.2 de Sequera Ortiz P, Pérez García R, Molina Nuñez M, Muñoz González RI, Álvarez Fernández G, Mérida Herrero E, Camba Caride MJ, Blázquez Collado LA, Alcaide Lara MP, Echarri Carrillo R; en representación del grupo del estudio ABC-treat; Grupo del estudio ABC-treat. Prospective randomised multicentre study to demonstrate the benefits of haemodialysis without acetate (with citrate): ABC-treat Study. Acute effect of citrate. Nefrologia (Engl Ed). 2019 Jul - Aug;39(4):424 - 433. English, Spanish. doi: 10.1016/j.nefro.2018.11.002. Epub 2019 Jan 24. PMID: 30686542.3 Grundström G, Christensson A, Alquist M, Nilsson LG, Segelmark M. Replacement of acetate with citrate in dialysis fluid: a randomized clinical trial of short-term safety and fluid
biocompatibility. BMC Nephrol. 2013 Oct 9;14:216. doi: 10.1186/1471-2369-14-216. PMID: 24103587; PMCID: PMC41247274 Molina Nuñez M, de Alarcón R, Roca S, Álvarez G, Ros MS, Jimeno C, Bucalo L, Villegas I, García MÁ. Citrate versus acetate-based dialysate in on-line haemodiafiltration: a prospective cross-over study. Blood Purif. 2015;39(1 - 3):181 - 187. doi: 10.1159/000371569. PMID: 25791278.5 Sands JJ, Kotanko P, Segal JH, Ho CH, Usvat L, Young A, Carter M, Sergeyeva O, Korth L, Maunsell E, Zhu Y, Krishnan M, Diaz-Buxo JA. Effects of citrate acid concentrate (Citrasate®) on heparin N requirements and hemodialysis adequacy: a multicenter, prospective noninferiority trial. Blood Purif. 2012;33(1 - 3):199 - 204. doi: 10.1159/000334157. Epub 2012 Jan 20. PMID: 22269855.6 Data on file: Medical Safety Data Sheet, Number 0056-0412 MSDS.